The final weekend of the 2025 NFL regular season features high-stakes matchups that will determine division champions and the last playoff spots, with the NFC West title and AFC North crown both hanging in the balance.
Saturday's primetime showdown pits the Seattle Seahawks against the San Francisco 49ers at Levi's Stadium in a winner-take-all battle for the NFC West championship. Kickoff is scheduled for 8 p.m. Eastern Time. The stakes couldn't be higher—the winner claims the division title, the No. 1 seed in the NFC, and a crucial first-round bye in the playoffs.
Both teams enter the contest having already secured playoff berths, but the difference between the top seed and a wild card spot is significant. Home-field advantage throughout the NFC playoffs and an extra week of rest could prove decisive in the quest for a Super Bowl appearance.
The NFC South race also concludes on Saturday, with the Carolina Panthers hosting the Tampa Bay Buccaneers at 4:30 p.m. Eastern. The Panthers control their destiny with a 3-1 record against divisional opponents, but the Buccaneers remain mathematically alive and need a victory combined with a Saints loss on Sunday.
Sunday's marquee matchup features the Pittsburgh Steelers hosting the Baltimore Ravens on Sunday Night Football at 8:20 p.m. Eastern on NBC. This rivalry game carries enormous implications—the winner secures the AFC North division title and a playoff berth, while the loser is eliminated from postseason contention entirely.
Twelve teams have already clinched playoff spots heading into Week 18, including the Denver Broncos, New England Patriots, Chicago Bears, Jacksonville Jaguars, Philadelphia Eagles, Houston Texans, Los Angeles Chargers, Los Angeles Rams, Buffalo Bills, and Green Bay Packers.
Looking ahead, the NFL playoff schedule begins with Wild Card Weekend on January 10-12, followed by the Divisional Round on January 17-18 and the Conference Championships on January 25. Super Bowl 60 is scheduled for February 8, 2026, at Levi's Stadium in Santa Clara, California—the same venue hosting Saturday's pivotal 49ers-Seahawks showdown.
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